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- $Unique_ID{BRK01880}
- $Pretitle{}
- $Title{Aspirin: Correct Dosage for Heart Disease}
- $Subject{Aspirin dose Dosage Heart Disease diseases atherosclerosis
- Physician's Health Study risk risks platelet platelets clot clotting blood
- protect protection protective react reaction reactions effect effects side
- adverse heartburn abdominal stomach ache pain discomfort gastritis peptic
- ulcer ulcers}
- $Volume{}
- $Log{
- Artherosclerosis of Arteries*0009301.scf
- Complications of Atherosclerosis*0009401.scf
- Risk Factors of Atherosclerosis*0009302.scf}
-
- Copyright (c) 1993 Tribune Media Services, Inc.
-
-
- Aspirin: Correct Dosage for Heart Disease
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-
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-
- QUESTION: My husband's doctor has him on a daily aspirin for his heart
- condition. That's made me very attentive to all the stories that are written
- about this in all the papers. That is where I have become confused. Could
- you please tell me how a simple aspirin is supposed to work in cases like
- this, and just what the right dose is? Everyone seems to have a different
- opinion. Thank you for your help.
-
- ------------------------------------------------------------------------------
-
- ANSWER: I suppose I could provide you with a totally valid answer, and advise
- that you follow your own doctor's counsel. After all, he does know your
- husband's condition better than I do, but somehow I don't think that is the
- intent of your question. So let's approach your question from a different
- perspectives, and furnish you with as much of the background information as I
- can. The interest in the use of aspirin in heart disease and atherosclerosis
- dramatically increased after the publication of the Physician's Health Study,
- in which more than 22,000 male physicians participated. In that study, the
- physicians who took a single 325 mg aspirin (the dose contained in a regular
- over-the-counter variety of aspirin) every other day apparently reduced their
- risk of a fatal heart attack by 66 percent. The results were explained by the
- action of aspirin which reduces the ability of platelets to clump, the first
- action in clot formation in the blood.
- Since that time there have been other studies, some confirming this
- effect, others that failed to do so. Different aspirin doses were used in
- some studies, but overall, the protective effects of aspirin were judged to be
- real. Since some people experience serious side effects from aspirin, such as
- heartburn, abdominal pain and discomfort, gastritis and peptic ulcer disease,
- it is felt that the lowest possible dose should be used. And that is where
- some of the confusion exists.
- At present several doses are used for this indication. A commonly used
- regimen prescribes a single 325 mg aspirin tablet daily, while many doctors
- prefer giving their patients this dose on an every other day schedule.
- Because this may be confusing, some doctors prefer using 1/2 an aspirin, or
- the smaller sized aspirins that contain only 160 mg, on a daily basis. Recent
- investigation have shown that daily doses as low as 40 - 70 mg may also be
- effective, with a greatly reduced chance of side effects. So you see, in the
- final analysis your own doctor's judgement is probably the most sound.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-